The all-time puzzle classic returns for the Wii generation, featuring online gameplay and a new Germ Buster mode! Destroy all the viruses trapped in the bottle by dropping and slotting capsules to create lines of matching colours. The more viruses you clear, the faster the capsules drop.

In Dr. Mario, challenge the computer in 1 Player mode, go head-to-head with a friend in 2 Player mode, or prove your skills against the world via Nintendo Wi-Fi Connection. You can also send a demo version of the game to a friend (within your region) using WiiConnect24.

In Germ Buster (based on the relaxation game in More Brain Training from Dr Kawashima), up to four players can use their Wii Remotes to grab, spin and slot capsules as your Miis try to keep the nasty bugs at bay. Who thought that catching germs could be so much fun?